(July 13, 2020)
QualDerm-affiliated physician, E. Eugene Bain III, MD, is among a group of physicians whose work Use of Adjuvant Radiotherapy in the Treatment of High-risk Cutaneous Squamous Cell Carcinoma With Perineural Invasion* was recently published online in JAMA Dermatology.
The study was conducted at New York University from January 1, 2005, to December 31, 2014, and included 31 patients. According to the publication, “Patients with histologically confirmed cSCC with perineural invasion were referred to radiation oncology services for consideration of adjuvant radiotherapy based on the presence of large-caliber perineural invasion (≥0.1 mm in diameter) or small-caliber perineural invasion (<0.1 mm) with additional high-risk features.”
All patients in the study were treated with Mohs micrographic surgery. While all patients were recommended for adjuvant radiotherapy, only 15 chose to complete the treatment. The results showed a 100% estimated 5-year disease-free survival rate for patients who received the adjuvant radiotherapy treatment compared to a 68.8% estimated 5-year disease-free survival rate for those who did not receive the treatment.
Dr. Bain is a board-certified dermatologist and fellowship-trained Mohs surgeon. He founded Raleigh-based Bain Dermatology in 2014. In 2018, Bain Dermatology affiliated with The Skin Surgery Center, a partner of QualDerm.
* Use of Adjuvant Radiotherapy in the Treatment of High-risk Cutaneous Squamous Cell Carcinoma With Perineural Invasion
Mary L. Stevenson, MD; Maressa C. Criscito, MD; Reason Wilken, MD; Nicole A. Doudican, PhD; Earl Eugene Bain III, MD; Bhupesh Parashar, MD; John A. Carucci, MD, PhD
JAMA Dermatol. Published online July 1, 2020. doi:10.1001/jamadermatol.2020.1984